Crohn’s Disease

Crohn’s Disease (CD) Is Unpredictable, With Symptoms and Severity Varying Among Patients1

780,000 Americans have Crohn's disease graphic

CD is a chronic inflammatory condition of the gastrointestinal tract.
Symptoms may include1:

  • Diarrhea
  • Rectal bleeding
  • Unexplained weight loss
  • Fever
  • Abdominal pain and cramping
  • Fatigue
  • Low energy
  • Reduced appetite

Patients with CD go through active flare periods and remission, and flare symptoms make it difficult for patients to keep a routine.1

There is no cure for CD, but patients can manage symptoms with a variety of medications1,2

Aminosalicylates (5-ASA)
Not specifically approved by the FDA, these agents decrease inflammation in the GI tract
Corticosteroids
Corticosteroids suppress the immune system in moderate-to-severe CD
Immuno- modulators
These agents modulate immune system response
Antibiotics
Antibiotics are used to treat bacterial infections in the GI tract
Biologics
Biologics may be an option for patients who have not responded to conventional therapy
  • TNFi biosimilars are now available. The FDA ensures that biosimilars and Interchangeable biosimilars are as safe and effective as their reference biologic treatments3
    • Only Interchangeable biosimilars may be auto-substituted for the reference product by a pharmacist
Learn more about a clinical trial of a biosimilar that demonstrated equivalence in terms of pharmacokinetics, safety, and efficacy to current treatment options